Experiments and discussions on how hydrogen molecules can prevent premature birth
- Sep 10, 2024
- 3 min read
From medical research around the world, it can be found that the free radical scavenging and anti-inflammatory effects of hydrogen molecules are obvious to all, and can be used in many fields such as health care, beauty, and sports.
The latest study "Effect of molecular hydrogen on uterine inflammation during preterm labor" by the research team of Professor Tomoko Nakano of Nagoya University points out that hydrogen molecules have a positive effect on prolonging pregnancy and preventing premature birth.
Why premature birth?
A birth that occurs after 20 weeks of pregnancy but less than 37 weeks is considered premature birth. The incidence of premature birth accounts for about 8 to 10% of all pregnancies. Because they are born before they have been in the mother's womb for a full number of weeks, premature babies are prone to health problems such as extremely low weight, hyperjaundice, sepsis, and respiratory diseases; even , deaths of premature infants account for 80% of all neonatal deaths.
Faced with such a problem, all parents are wondering, why does premature birth occur? Is there any way to prevent it? Many studies in modern medicine have shown that inflammation within the mother's uterus may be the main cause of premature birth. So, does hydrogen molecule, the "anti-inflammatory nemesis", help premature birth caused by uterine inflammation?
Experiments on the prevention of premature birth by hydrogen molecules
In order to study the relationship between hydrogen molecules and the prevention of premature birth, Japanese scholars conducted two sets of experiments on 38 pregnant experimental rats aged between 8 and 10 weeks. The uterus of experimental mice was inflamed by injecting lipopolysaccharide (LPS) physiological saline, and the uterine condition and delivery time of the experimental mice were observed. Lipopolysaccharide (LPS) is a major part of the outer membrane of Gram-negative bacteria and is an endotoxin that may cause a strong immune response and cause acute inflammation.
[Experiment 1] Divide 20 experimental mice into 2 groups, with 10 experimental mice in each group: the lipopolysaccharide group and the lipopolysaccharide hydrogenated water group. Both groups were injected with physiological saline with a lipopolysaccharide (LPS) concentration of 500 mg per kilogram on the 15.5th day of pregnancy; only the lipopolysaccharide hydrogenated water group was allowed to start drinking 0.2uM concentration on the 14.5th day of pregnancy. of hydrogen water.
After injecting lipopolysaccharide saline, the research team observed the delivery time of experimental mice and found that (1) the average time from injection of lipopolysaccharide to delivery was 18.2 hours for experimental rats in the lipopolysaccharide group, (2) while those in the lipopolysaccharide hydrogenated water group The average time is 33.5 hours.
This result shows that hydrogen water can effectively relieve premature labor caused by uterine inflammation.
[Experiment 2]
Divide 18 experimental mice into 3 groups, with 6 experimental mice in each group: control group, lipopolysaccharide group and lipopolysaccharide hydrogenated water group, and intraperitoneally inject the same dose and concentration of LPS (500 mg per kilogram) ), physiological saline with different contents to the uterus of experimental rats.
o Control group: On the 15.5th day of pregnancy, the experimental mice were injected with normal saline solution without lipopolysaccharide (LPS).
o Lipopolysaccharide group: On the 15.5th day of pregnancy, the experimental mice were injected with normal saline solution containing lipopolysaccharide (LPS).
Polysaccharide hydrogenated water group: On the 14.5th day of pregnancy, the experimental rats were allowed to drink hydrogenated water with a concentration of 0.2uM, and were injected with physiological saline containing lipopolysaccharide (LPS) the next day (day 15.5).
After applying physiological saline, the research team euthanized the experimental mouse, collected and observed the uterine tissue of the experimental mouse. The research team also found that the protein expression that promotes uterine contraction and the inflammatory factors Tnf, II6, II8, etc. were significantly higher in the uterus of experimental mice in the lipopolysaccharide group than in the lipopolysaccharide hydrogenated water group.
From the above two experiments, we can know that hydrogen molecules can prolong the pregnancy period of experimental mice with uterine inflammation by inhibiting the expression of proteins that promote uterine contraction and soothing uterine inflammation.
This research paper also mentioned that the effect of hydrogen molecules on premature birth is "prevention" . Therefore, if pregnant mothers can start to be exposed to hydrogen health care before acute inflammation of the uterus, they will rely on hydrogen molecules to reduce inflammation after the inflammation. More effective!